SCHEMBL10437293

SCHEMBL10437293

C=C(C)C(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)C(=C)C)cc2OCCC)c(OCCC)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.39
KMT2A Q03164 2/20 0.36
ATM Q13315 1/20 0.36
ACACB O00763 4/20 0.36
CA9 Q16790 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PLK1 P53350 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639822 0.90 KDM4E (0.43) ELANEKMT2AATMCA9MTNR1A
SCHEMBL23581567 0.85 ELANE (0.36) ELANEKMT2AATMHTTPOLB
SCHEMBL9173944 0.83 THRB (0.47) KMT2ACA9HTTMAPTL3MBTL1
SCHEMBL30603971 0.83 THRB (0.47) KMT2ACA9HTTMAPTL3MBTL1
SCHEMBL15495752 0.83 ELANE (0.41) ELANEKMT2AATMCA9MTNR1A
SCHEMBL10880955 0.83 ELANE (0.34) ELANEKMT2AATMHTTPOLB
SCHEMBL346348 0.82 ELANE (0.37) ELANEKMT2AATMHTTPOLB
SCHEMBL11108090 0.82 ELANE (0.33) ELANEKMT2AATML3MBTL1GAA
SCHEMBL10987623 0.81 ELANE (0.38) ELANEKMT2AATMHTTPOLB
SCHEMBL27324820 0.81 TSHR (0.42) ELANEKMT2AATMCA9MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385456-A2 High surface hardness transparent resin and polymerizable monomer MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-09-05 EP disclosed