SCHEMBL346348

SCHEMBL346348

C=C(C)C(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)C(=C)C)cc2OCC(C)O)c(OCC(C)O)c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.37
KMT2A Q03164 2/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 2/20 0.34
CYP2C19 P33261 1/20 0.34
TSHR P16473 1/20 0.32
POLB P06746 3/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10880955 0.90 ELANE (0.34) ELANEKMT2AATMLMNAPOLB
SCHEMBL23581567 0.88 ELANE (0.36) ELANEKMT2AATMLMNAPOLB
SCHEMBL10880960 0.86 ELANE (0.34) ELANEKMT2AATMPOLB
SCHEMBL4639822 0.85 KDM4E (0.43) ELANEKMT2AATMLMNATSHR
SCHEMBL6054116 0.84 THRB (0.39) ELANEKMT2ALMNACYP2C19TSHR
SCHEMBL29771152 0.83 ELANE (0.41) ELANEKMT2AATMPOLBKDM4E
SCHEMBL65219 0.83 ELANE (0.41) ELANEKMT2AATMPOLBKDM4E
SCHEMBL10437293 0.82 ELANE (0.39) ELANEKMT2AATMPOLBAPEX1
SCHEMBL10873359 0.81 LMNA (0.36) KMT2ALMNACYP2C19TSHRPOLB
SCHEMBL8409499 0.80 TSHR (0.39) ELANEKMT2AATMLMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7584630-B2 Photochromic ocular devices TRANSITIONS OPTICAL, INC. (US) 2009-09-08 US claimed
EP-1604231-B9 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2009-01-07 EP claimed
EP-1604231-B1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2008-07-02 EP claimed
US-20070113587-A1 Photochromic ocular devices TRANSITIONS OPTICAL LIMITED (IE) 2007-05-24 US claimed
US-20040186241-A1 Photochromic ocular devices TRANSITIONS OPTICAL, INC. 2004-09-23 US claimed
US-5942303-A CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES NOF CORPORATION (JP) 1999-08-24 US claimed
EP-0012948-B1 SCRATCH-RESISTANT, DYEABLE COATING COMPOSITIONS FOR SYNTHETIC RESIN ARTICLES MITSUBISHI RAYON CO., LTD. (JP) 1983-02-02 EP claimed
US-4291097-A PHOTOPOLYMERIZATION OF AN ACRYLIC ESTER MIXTURE WITH PHOSPHORIC ACID ESTER AND AN ETHANOLAMINE MITSUBISHI RAYON CO., LTD. (JP) 1981-09-22 US claimed
EP-0012948-A1 Scratch-resistant, dyeable coating compositions for synthetic resin articles MITSUBISHI RAYON CO., LTD. (JP) 1980-07-09 EP claimed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
EP-4378967-A1 (METH)ACRYLAMIDE COMPOUND, MONOMER COMPOSITION, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2024-06-05 EP disclosed
US-11981763-B2 Resin composition for stereolithographic modeling KURARAY NORITAKE DENTAL INC. (JP) 2024-05-14 US disclosed
US-20240122814-A1 DENTAL ADHESIVE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2024-04-18 US disclosed
EP-4327798-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2024-02-28 EP disclosed
EP-0012948-B1 SCRATCH-RESISTANT, DYEABLE COATING COMPOSITIONS FOR SYNTHETIC RESIN ARTICLES MITSUBISHI RAYON CO., LTD. (JP) 1983-02-02 EP disclosed
EP-0057906-A1 Coating composition and process for preparing synthetic resin shaped articles by using same MITSUBISHI RAYON CO., LTD. (JP) 1982-08-18 EP disclosed
US-4339474-A POLYFUNCTIONAL ACRYLATE, MONO- OR DIACRYLATE, ULTRAVIOLET ABSORBER, PHOTOINITIATOR MITSUBISHI RAYON COMPANY, LTD. (JP) 1982-07-13 US disclosed
US-4291097-A PHOTOPOLYMERIZATION OF AN ACRYLIC ESTER MIXTURE WITH PHOSPHORIC ACID ESTER AND AN ETHANOLAMINE MITSUBISHI RAYON CO., LTD. (JP) 1981-09-22 US disclosed
EP-0035272-A1 Coating composition and process for preparing synthetic resin shaped articles by using same MITSUBISHI RAYON CO., LTD. (JP) 1981-09-09 EP disclosed
EP-0012948-A1 Scratch-resistant, dyeable coating compositions for synthetic resin articles MITSUBISHI RAYON CO., LTD. (JP) 1980-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL ELANE 2345/4885KMT2A 1501/4885ATM 3316/4885
US-20240122814-A1 DENTAL ADHESIVE COMPOSITION ITGA1, ILK, CAD ELANE 821/4885KMT2A 2392/4885ATM 1081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.