SCHEMBL10437883

SCHEMBL10437883

CC(C)(C)c1nn(-c2cc(O)c(Cl)cc2F)c(=O)o1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPOX P50336 19/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
NR1I2 O75469 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11130699 0.88 PPOX (0.64) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL31448249 0.87 PPOX (0.53) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL31448252 0.87 PPOX (0.53) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL11545684 0.85 PPOX (0.51) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL31448172 0.84 MEN1 (0.49) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL31448223 0.82 PPOX (0.52) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL10437969 0.82 PPOX (0.61) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL10553808 0.80 PPOX (0.81) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL10553270 0.79 PPOX (0.47) PPOXMEN1KMT2ATDP1NR1I2
SCHEMBL6967744 0.77 PPOX (0.43) PPOXMEN1KMT2ATDP1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274249-A1 Oxadiazolone derivative, production process thereof, and herbicide containing same RHONE-POULENC AGROCHIMIE (FR) 1988-07-13 EP claimed
WO-1988004653-A1 OXADIAZOLONE DERIVATIVE, PRODUCTION PROCESS THEREOF, AND HERBICIDE CONTAINING SAME SHOWA RHODIA CHEMICALS KABUSHIKI KAISHA (JP) 1988-06-30 WO claimed
JP-63150267-A None JP disclosed
EP-0354622-A1 Oxadiazolone herbicides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-02-14 EP disclosed
US-4842640-A HIGH ACTIVITY; RICE RHONE-POULENC AGROCHIMIE (FR) 1989-06-27 US disclosed
EP-0274249-A1 Oxadiazolone derivative, production process thereof, and herbicide containing same RHONE-POULENC AGROCHIMIE (FR) 1988-07-13 EP disclosed
WO-1988004653-A1 OXADIAZOLONE DERIVATIVE, PRODUCTION PROCESS THEREOF, AND HERBICIDE CONTAINING SAME SHOWA RHODIA CHEMICALS KABUSHIKI KAISHA (JP) 1988-06-30 WO disclosed
JP-S63150267-A OXADIAZOLONE DERIVATIVE AND HERBICIDE SHOWA ROODEIA KAGAKU KK 1988-06-22 JP disclosed