Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 19/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130699 | 0.88 | PPOX (0.64) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL10437883 | 0.85 | PPOX (0.51) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL11545462 | 0.80 | NPSR1 (0.39) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL9378668 | 0.76 | PPOX (0.56) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL11272220 | 0.76 | MEN1 (0.60) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL11575267 | 0.74 | PPOX (0.32) | PPOX | |
| SCHEMBL6967744 | 0.72 | PPOX (0.43) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL31448252 | 0.71 | PPOX (0.53) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL31448249 | 0.71 | PPOX (0.53) | PPOXMEN1KMT2ATDP1NR1I2 | |
| SCHEMBL11848214 | 0.71 | MEN1 (0.72) | PPOXMEN1KMT2ATDP1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138404-A | Process for the preparation of oxadiazolines | RHONE-POULENC S.A. (FR) | 1979-02-06 | — | — | US | disclosed |
| US-3941798-A | 5-Alkyl-3-(2-hydroxylamino-4-chlorophenyl)-1,3,4-oxadiazolin-2-one compounds | RHONE POULENC S.A. (FR) | 1976-03-02 | — | — | US | disclosed |