Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.52 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.52 |
| ▸ | INPP5B | P32019 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30770359 | 0.82 | INPPL1 (0.57) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL19808 | 0.82 | INPPL1 (0.57) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL8386747 | 0.81 | INPPL1 (0.68) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL2541603 | 0.81 | INPPL1 (0.50) | INPPL1INPP5AINPP5BIDO1AKT1 | |
| SCHEMBL9445083 | 0.81 | IDO1 (0.50) | PLK1IDO1EP300KAT8HPGDS | |
| SCHEMBL11740599 | 0.80 | INPPL1 (0.55) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL2547022 | 0.79 | IDO1 (0.53) | INPPL1INPP5AINPP5BIDO1AKT1 | |
| SCHEMBL419307 | 0.78 | IDO1 (0.73) | PLK1IDO1EP300KAT8HPGDS | |
| SCHEMBL29380721 | 0.78 | IDO1 (0.73) | PLK1IDO1EP300KAT8HPGDS | |
| SCHEMBL21585533 | 0.78 | INPPL1 (0.47) | INPPL1INPP5AINPP5BIDO1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350808-A2 | Method for detecting substances with hydrolase activity | Roche Diagnostics GmbH (DE) | 1990-01-17 | — | — | EP | disclosed |