SCHEMBL419307

SCHEMBL419307

COc1ccc(OC)c2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.73
EP300 Q09472 1/20 0.70
KAT8 Q9H7Z6 1/20 0.70
IMPDH2 P12268 1/20 0.64
IMPDH1 P20839 1/20 0.64
NQO1 P15559 1/20 0.64
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA12 O43570 1/20 0.61
CA4 P22748 1/20 0.61
CA14 Q9ULX7 1/20 0.61
MAPT P10636 3/20 0.58
PLK1 P53350 1/20 0.55
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 1/20 0.55
MAPK1 P28482 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HPGDS O60760 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380721 1.00 IDO1 (0.73) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL31666411 0.92 IDO1 (0.64) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL12019777 0.92 IDO1 (0.64) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL12019841 0.92 IDO1 (0.64) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL7753164 0.92 IDO1 (0.64) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL357145 0.88 CA1 (0.61) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL31116611 0.88 CA1 (0.61) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL1802600 0.87 IDO1 (0.59) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL2091118 0.87 IDO1 (0.59) IDO1EP300KAT8IMPDH2IMPDH1
SCHEMBL637626 0.87 CYP1A2 (0.62) IDO1EP300KAT8IMPDH2IMPDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 862 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868148-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-11-10 CN claimed
CN-107868155-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
US-9991542-B2 Two-electron high potential and high capacity redox active molecules for energy storage applications UCHICAGO ARGONNE, LLC (US) 2018-06-05 US claimed
EP-2257515-B1 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF CENTRE NAT RECH SCIENT (FR) 2017-05-17 EP claimed
US-20170062863-A1 TWO-ELECTRON HIGH POTENTIAL AND HIGH CAPACITY REDOX ACTIVE MOLECULES FOR ENERGY STORAGE APPLICATIONS UCHICAGO ARGONNE, LLC 2017-03-02 US claimed
CN-102939321-B Stabilized polyene-polythiol curing resin composition SHOWA DENKO KK 2014-07-09 CN claimed
US-20110059972-A1 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-03-10 US claimed
EP-0439148-B1 Heat-sensitive recording material NEW OJI PAPER CO LTD (JP) 1994-12-28 EP claimed
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
US-5116802-A Basic fluoran dye and di-(p-methylbenzyl)oxalate KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-05-26 US claimed
EP-0439148-A1 Heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1991-07-31 EP claimed
EP-0345755-A2 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1989-12-13 EP claimed
US-4600537-A ANTITUMOR AGENTS, CARBONYLATION FARMITALIA CARLO ERBA S.P.A. (IT) 1986-07-15 US claimed
JP-62280072-A None JP disclosed
JP-61164884-A None JP disclosed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
US-4540814-A 1,4-Dimethoxy naphthalenecarboxamide anticonvulsants ADRIA LABORATORIES, INC. (US) 1985-09-10 US disclosed
US-4465671-A ANTI-LEUKEMIA AGENTS FARMITALIA CARLO ERBA S.P.A. (IT) 1984-08-14 US disclosed
EP-0013577-B1 PROCESS FOR THE PREPARATION OF HEXAHYDRONAPHTHACENE DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-09-28 EP disclosed
US-4229274-A PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS PPG INDUSTRIES, INC. (US) 1980-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059972-A1 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF NQO1, NDUFV2, RECQL IDO1 3244/4885EP300 1664/4885KAT8 3114/4885
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA IDO1 2957/4885EP300 2984/4885KAT8 2837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.