Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 4/20 | 0.57 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.57 |
| ▸ | INPP5B | P32019 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30770359 | 1.00 | INPPL1 (0.57) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL11740599 | 0.98 | INPPL1 (0.55) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL2573126 | 0.89 | INPPL1 (0.70) | INPPL1INPP5AINPP5BSRCHPGD | |
| SCHEMBL28621325 | 0.87 | CA1 (0.56) | CA1CA2CA12CA4CA7 | |
| SCHEMBL28074543 | 0.85 | CA1 (0.54) | CA1CA2CA12CA4CA7 | |
| SCHEMBL11253571 | 0.83 | CA1 (0.52) | CA1CA2CA12CA4CA7 | |
| SCHEMBL19809 | 0.82 | CA1 (0.62) | CA1CA2CA12CA4CA7 | |
| SCHEMBL10438501 | 0.82 | PLK1 (0.53) | INPPL1INPP5AINPP5BSRCHPGD | |
| SCHEMBL9701188 | 0.82 | INPPL1 (0.68) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL29137787 | 0.79 | CA1 (0.52) | INPPL1INPP5AINPP5BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021054927-A2 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2021-03-25 | — | — | WO | claimed |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2020-02-13 | — | — | US | claimed |
| US-9622969-B2 | Polymer conjugated protein micelles | SOUTH DAKOTA STATE UNIV (US) | 2017-04-18 | — | — | US | claimed |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | SOUTH DAKOTA STATE UNIVERSITY (US) | 2014-12-18 | — | — | US | claimed |
| EP-2729136-A1 | DRUG COMBINATIONS AND USES IN TREATING A COUGHING CONDITION | Biocopea Limited (GB) | 2014-05-14 | — | — | EP | claimed |
| CN-103648488-A | Pharmaceutical compositions and use in treating cough conditions | BIOCOPEA LTD | 2014-03-19 | — | — | CN | claimed |
| EP-2608847-A1 | THEOBROMINE IN COMBINATION WITH AN EXPECTORANT OR A MUCOLYTIC FOR USE IN THERAPY | Biocopea Limited (GB) | 2013-07-03 | — | — | EP | claimed |
| WO-2013004999-A1 | DRUG COMBINATIONS AND USES IN TREATING A COUGHING CONDITION | BIOCOPEA LIMITED (GB) | 2013-01-10 | — | — | WO | claimed |
| WO-2012025761-A1 | THEOBROMINE IN COMBINATION WITH AN EXPECTORANT OR A MUCOLYTIC FOR USE IN THERAPY | BIOCOPEA LIMITED (GB) | 2012-03-01 | — | — | WO | claimed |
| CN-112940644-B | Cellulose acetate wood filler composition | 醋酸纤维国际有限责任公司 | 2022-03-08 | — | — | CN | disclosed |
| EP-2214716-B1 | HYDROXYAPATITE-TARGETING MULTIARM POLYMERS AND CONJUGATES MADE THEREFROM | NEKTAR THERAPEUTICS (US) | 2021-11-17 | — | — | EP | disclosed |
| US-11142524-B2 | Substituted-3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and stimulator for interferon genes (STING) modulators as cancer immunotherapeutics | Stingray Therapeutics, Inc. (US) | 2021-10-12 | — | — | US | disclosed |
| CN-112940644-A | Cellulose acetate wood filler composition | 醋酸纤维国际有限责任公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-108291123-B | Cellulose acetate wood filler composition | 醋酸纤维国际有限责任公司 | 2021-04-23 | — | — | CN | disclosed |
| US-20020035217-A1 | Hyperbranched polymeric micelles for encapsulation and delivery of hydrophobic molecules | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2002-03-21 | — | — | US | disclosed |
| EP-1176983-A2 | HYPERBRANCHED POLYMERIC MICELLES FOR ENCAPSULATION AND DELIVERY OF HYDROPHOBIC MOLECULES | RUTGERS, THE STATE UNIVERSITY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-20020013331-A1 | Methods and compositions for treating pain of the mucous membrane | WILLIAMS ROBERT O (US) | 2002-01-31 | — | — | US | disclosed |
| WO-2002000195-A2 | METHODS AND COMPOSITIONS FOR TREATING PAIN OF THE MUCOUS MEMBRANE | EPICEPT CORPORATION (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2000065024-A2 | HYPERBRANCHED POLYMERIC MICELLES FOR ENCAPSULATION AND DELIVERY OF HYDROPHOBIC MOLECULES | RUTGERS, THE STATE UNIVERSITY (US) | 2000-11-02 | — | — | WO | disclosed |
| EP-0055313-A1 | Guaiacol and derivatives; compositions thereof and use in a method of treatment | ED. GEISTLICH SÖHNE AG FÜR CHEMISCHE INDUSTRIE (CH) | 1982-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | GSTK1, GSTO1, GSTM2 | INPPL1 1292/4885INPP5A 4099/4885INPP5B 2070/4885 |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | MTDH, PSMG3, GHITM | INPPL1 2470/4885INPP5A 1189/4885INPP5B 1915/4885 |
| US-11142524-B2 | Substituted-3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and stimulator for interferon genes (STING) modulators as cancer immunotherapeutics | STING1, ENPP1, CGAS | INPPL1 21/4885INPP5A 108/4885INPP5B 51/4885 |
| US-20020013331-A1 | Methods and compositions for treating pain of the mucous membrane | MUC1, TRPV1, TAS2R60 | INPPL1 2215/4885INPP5A 961/4885INPP5B 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.