Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 8/20 | 0.50 |
| ▸ | GSK3A | P49840 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | PMM2 | O15305 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306506 | 0.84 | MAPK1 (0.71) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL12660977 | 0.79 | MAPK1 (0.65) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL26558990 | 0.77 | MAPK1 (0.62) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL13310390 | 0.75 | MAPK1 (0.74) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL12563173 | 0.74 | MAPK1 (0.59) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL1730607 | 0.73 | MAPK1 (0.58) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL10607179 | 0.73 | MAPK1 (0.71) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL1722780 | 0.73 | GSK3B (0.71) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL8209629 | 0.71 | MAPK1 (0.56) | MAPK1GSK3BGSK3AGAAL3MBTL1 | |
| SCHEMBL14505675 | 0.71 | MAPK1 (0.75) | MAPK1GSK3BGSK3AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379228-A2 | Process for the preparation of polymers containing imide groups from bis-imides and alkenyloxyanilines | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | claimed |
| EP-0273839-A2 | Polyimides derived from bis-imides and alkenyl-oxyanilines | RHONE-POULENC CHIMIE (FR) | 1988-07-06 | — | — | EP | claimed |