Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 6/20 | 0.46 |
| ▸ | GSK3B | P49841 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12660977 | 0.85 | MAPK1 (0.65) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL5306506 | 0.80 | MAPK1 (0.71) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL8208644 | 0.77 | MAPK1 (0.56) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL10607179 | 0.74 | MAPK1 (0.71) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL14505675 | 0.73 | MAPK1 (0.75) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL10438652 | 0.71 | MAPK1 (0.60) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL13310390 | 0.71 | MAPK1 (0.74) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL23312315 | 0.71 | PDE7A (0.49) | MAPK1GSK3AGSK3BGAAALDH1A1 | |
| SCHEMBL22680260 | 0.71 | MAPK1 (0.53) | MAPK1GSK3AGSK3BGAANPSR1 | |
| SCHEMBL22680259 | 0.70 | MAPK1 (0.43) | MAPK1GSK3AGSK3BGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046342-A | 3, 6-bis[4-(alkyloxy) phenyloxy] pyromellitic dianhydrides and process for preparing the same | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2000-04-04 | — | — | US | disclosed |