SCHEMBL26558990

SCHEMBL26558990

O=c1c2c3c(=O)n(-c4ccccc4)c(=O)c3c3c(=O)n(-c4ccc(-n5c(=O)c6c7c(=O)n(-c8ccccc8)c(=O)c7c7c(=O)n(-c8ccccc8)c(=O)c7c6c5=O)cc4)c(=O)c3c2c(=O)n1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.62
GSK3A P49840 6/20 0.52
GSK3B P49841 6/20 0.52
GAA P10253 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
NTRK1 P04629 1/20 0.46
IGF1R P08069 1/20 0.46
FGFR1 P11362 1/20 0.46
NTRK3 Q16288 1/20 0.46
NTRK2 Q16620 1/20 0.46
KMT2A Q03164 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
PGR P06401 1/20 0.42
KDM4E B2RXH2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12660977 0.97 MAPK1 (0.65) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL5306506 0.86 MAPK1 (0.71) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL8208644 0.83 MAPK1 (0.56) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL8209629 0.83 MAPK1 (0.56) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL10607179 0.80 MAPK1 (0.71) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL14505675 0.78 MAPK1 (0.75) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL12660985 0.77 MGLL (0.48) MAPK1GSK3AGSK3BL3MBTL1KDM4E
SCHEMBL13310390 0.77 MAPK1 (0.74) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL10438652 0.77 MAPK1 (0.60) MAPK1GSK3AGSK3BGAAL3MBTL1
SCHEMBL23312315 0.77 PDE7A (0.49) MAPK1GSK3AGSK3BGAANTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337445-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2023-10-19 US disclosed
US-20230337445-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2023-10-19 US disclosed