Phenylhydrazine

Phenylhydrazine

SCHEMBL1043907

NNc1ccccc1.O=CC(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.64
CYP1A2 P05177 2/20 0.64
LMNA P02545 2/20 0.64
CYP3A4 P08684 2/20 0.64
IDO1 P14902 2/20 0.64
CYP2D6 P10635 1/20 0.64
CYP2C9 P11712 1/20 0.64
CYP2C19 P33261 1/20 0.64
PTGS2 P35354 1/20 0.64
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TGM2 P21980 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylhydrazine SCHEMBL5581958 0.87 TDP1 (0.58) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL11361019 0.86 LMNA (0.64) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL11361010 0.86 LMNA (0.64) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL11666654 0.86 TDP1 (0.70) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL10867769 0.85 IDO1 (0.78) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL19875575 0.83 IDO1 (0.74) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL27469514 0.83 CYP3A4 (0.74) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL10719045 0.81 CYP3A4 (0.70) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL11810983 0.81 TDP1 (0.70) TDP1CYP1A2LMNACYP3A4IDO1
Phenylhydrazine SCHEMBL28131748 0.81 IDO1 (0.70) TDP1CYP1A2LMNACYP3A4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521433-A1 PROCESS FOR PRODUCING L-GLUTAMIC ACID AJINOMOTO CO., INC. (JP) 2019-08-07 EP disclosed
EP-3020807-B1 PROCESS FOR PRODUCING L-GLUTAMINE, L-GLUTAMIC ACID, L-ARGININE AND L-PROLINE AJINOMOTO KK (JP) 2019-04-10 EP disclosed
EP-3020807-A1 METHOD FOR MANUFACTURING USEFUL SUBSTANCE Ajinomoto Co., Inc. (JP) 2016-05-18 EP disclosed
US-20160130618-A1 Method for Manufacturing Useful Substance AJINOMOTO CO., INC. (JP) 2016-05-12 US disclosed
EP-2275529-A2 Process for the preparation of aspartate and derived amino acids employing a microorganism with enhanced glyoxylate shunt Metabolic Explorer (FR) 2011-01-19 EP disclosed
US-20080233617-A1 Process for the Preparation of a Aspartate and Derived Amino Acids Like Lysine, Threonine, Isoleucine, Methionine, or Homoserine Employing Microorganism with Enhanced Isocitrate Lyase and/or Malate Synthase Expression METABOLIC EXPLORER (FR) 2008-09-25 US disclosed
EP-1913128-A1 PROCESS FOR THE PREPARATION OF ASPARTATE AND DERIVED AMINO ACIDS LIKE LYSINE, THREONINE, ISOLEUCINE, METHIONINE, OR HOMOSERINE EMPLOYING A MICROORGANISM WITH ENHANCED ISOCITRATE LYASE AND/OR MALATE SYNTHASE EXPRESSION Metabolic Explorer (FR) 2008-04-23 EP disclosed
WO-2007017710-A1 PROCESS FOR THE PREPARATION OF ASPARTATE AND DERIVED AMINO ACIDS LIKE LYSINE, THREONINE, ISOLEUCINE, METHIONINE, HOMOSERINE, OR VALINE EMPLOYING A MICROORGANISM WITH ENHANCED ISOCITRATE LYASE AND/OR MALATE SYNTHASE EXPRESSION METABOLIC EXPLORER (FR) 2007-02-15 WO disclosed
WO-2007017526-A1 PROCESS FOR THE PREPARATION OF ASPARTATE AND DERIVED AMINO ACIDS LIKE LYSINE, THREONINE, ISOLEUCINE, METHIONINE, OR HOMOSERINE EMPLOYING A MICROORGANISM WITH ENHANCED ISOCITRATE LYASE AND/OR MALATE SYNTHASE EXPRESSION METABOLIC EXPLORER (FR) 2007-02-15 WO disclosed
EP-0660875-A4 METHODS FOR INCREASING CARBON CONVERSION EFFICIENCY IN MICROORGANISMS. NUTRASWEET CO (US) 1998-08-05 EP disclosed
EP-0660875-A1 METHODS FOR INCREASING CARBON CONVERSION EFFICIENCY IN MICROORGANISMS THE NUTRASWEET COMPANY (US) 1995-07-05 EP disclosed
WO-1994028154-A1 METHODS FOR INCREASING CARBON CONVERSION EFFICIENCY IN MICROORGANISMS THE NUTRASWEET COMPANY (US) 1994-12-08 WO disclosed