Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylhydrazine SCHEMBL1043907 | 0.87 | TDP1 (0.64) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Phenylhydrazine SCHEMBL10719045 | 0.87 | CYP3A4 (0.70) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Methylglyoxal SCHEMBL5582423 | 0.84 | TP53 (0.46) | TDP1TSHRNPC1RAB9AMAPT | |
| Phenylhydrazine SCHEMBL11810983 | 0.82 | TDP1 (0.70) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Phenylhydrazine SCHEMBL11666654 | 0.82 | TDP1 (0.70) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Phenylhydrazine SCHEMBL10867769 | 0.82 | IDO1 (0.78) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Phenylhydrazine SCHEMBL27469514 | 0.80 | CYP3A4 (0.74) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Phenylhydrazine SCHEMBL19875575 | 0.80 | IDO1 (0.74) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Phenylhydrazine SCHEMBL16763414 | 0.79 | TDP1 (0.82) | TDP1CYP3A4LMNACYP1A2CYP2D6 | |
| Acetophenone SCHEMBL28186726 | 0.79 | CYP1A2 (0.58) | TDP1CYP3A4LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | DYNAMIS THERAPEUTICS, INC. | 2007-03-22 | — | — | US | disclosed |
| US-5661139-A | FOR INHIBITING GLYCOSYLATION OF PROTEINS TO PREVENT DISCOLORATION OF THE TEETH | ALTEON INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996040622-A1 | BIS-(2-ARYL)HYDRAZONES AS INHIBITORS OF THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | FN3K, PDXK, COLGALT1 | TDP1 1427/4885CYP3A4 4738/4885LMNA 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.