SCHEMBL10439262

SCHEMBL10439262

O=C1c2ccccc2C(=O)N1OCCCCP(=O)(O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
RECQL P46063 1/20 0.51
ALDH1A1 P00352 4/20 0.49
CYP1A2 P05177 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
CYP2C9 P11712 1/20 0.45
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17635912 0.84 GAA (0.60) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL24507059 0.83 GAA (0.71) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL6570943 0.81 GAA (0.74) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL12513630 0.80 GAA (0.62) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL9683399 0.80 GAA (0.50) GAARECQLALDH1A1TDP1
SCHEMBL12244739 0.79 GAA (0.61) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL17770699 0.78 GAA (0.65) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL4853171 0.78 GAA (0.65) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL12058874 0.78 GAA (0.56) GAARECQLALDH1A1CYP1A2TDP1
SCHEMBL22326350 0.77 GAA (0.88) GAARECQLALDH1A1CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0374622-A2 3,4-Bis-(methylamino)-6-(2,3-dimethyl-2-butyl)-1,2,4-triazin-5(4H)-one, process for its preparation and its use as a herbicide BAYER AG (DE) 1990-06-27 EP disclosed