Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267310 | 1.00 | TDP1 (0.49) | TDP1SMN1; SMN2NPC1GAARAB9A | |
| SCHEMBL11253419 | 0.83 | KMT2A (0.41) | TDP1SMN1; SMN2NPC1RAB9AMGLL | |
| SCHEMBL11253395 | 0.83 | KMT2A (0.41) | TDP1SMN1; SMN2NPC1RAB9AMGLL | |
| SCHEMBL24130977 | 0.79 | NPC1 (0.47) | SMN1; SMN2NPC1GAARAB9ALMNA | |
| SCHEMBL3090232 | 0.76 | TAAR1 (0.40) | SMN1; SMN2NPC1GAARAB9ALMNA | |
| SCHEMBL3090233 | 0.76 | TAAR1 (0.40) | SMN1; SMN2NPC1GAARAB9ALMNA | |
| SCHEMBL8068468 | 0.73 | TDP1 (0.53) | TDP1SMN1; SMN2MGLLALDH1A1GLA | |
| SCHEMBL12176875 | 0.73 | ALDH1A1 (0.50) | TDP1SMN1; SMN2NPC1GAARAB9A | |
| SCHEMBL2592598 | 0.73 | ALDH1A1 (0.50) | TDP1SMN1; SMN2NPC1GAARAB9A | |
| SCHEMBL2592589 | 0.73 | ALDH1A1 (0.50) | TDP1SMN1; SMN2NPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369944-A1 | Substituted oxadiamino butanes | CIBA-GEIGY AG (CH) | 1990-05-23 | — | — | EP | disclosed |
| US-4358450-A | FOR DECREASING BLOOD CHOLESTEROL | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |
| US-4328227-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |