Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 8/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161965 | 0.89 | CAMK2A (0.57) | CLCN2CHRM4CHRM3CTSVCTSL | |
| SCHEMBL10439762 | 0.86 | CLCN2 (0.50) | CLCN2CHRM4CHRM3CTSVCTSL | |
| SCHEMBL7166218 | 0.81 | CAMK2A (0.57) | CLCN2CHRM4CHRM3CTSVCTSL | |
| SCHEMBL10439643 | 0.78 | BRD4 (0.52) | CLCN2CHRM4CHRM3KDM4EALDH1A1 | |
| SCHEMBL10439653 | 0.78 | CLCN2 (0.42) | CLCN2CHRM4CHRM3CTSVCTSL | |
| SCHEMBL7582466 | 0.74 | F2 (0.46) | CLCN2CHRM4CHRM3CTSVCTSL | |
| SCHEMBL10439814 | 0.73 | HTR1A (0.44) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7161922 | 0.70 | CAMK2A (0.64) | CLCN2CAMK2ACYP2C9PTGS2KMT2A | |
| SCHEMBL24021540 | 0.68 | CLCN2 (1.00) | CLCN2CHRM4CHRM3CTSVCTSL | |
| 3'-Hydroxy-4'-Methoxy-Diclofenac SCHEMBL7160787 | 0.68 | CAMK2A (0.64) | CLCN2CAMK2ACYP2C9PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377896-A2 | Cyclooxygenase and 5-lipoxygenase inhibiting hydroxamic acid derivatives | CIBA-GEIGY AG (CH) | 1990-07-18 | — | — | EP | disclosed |