Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | F7 | P08709 | 5/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573747 | 0.92 | F2 (0.46) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10439643 | 0.81 | BRD4 (0.52) | CHRM4CHRM3CLCN2KDM4EALDH1A1 | |
| SCHEMBL7583004 | 0.81 | ALDH1A1 (0.42) | ATMKDM4EALDH1A1 | |
| SCHEMBL7164900 | 0.78 | ALDH1A1 (0.43) | CLCN2ATMKDM4EALDH1A1 | |
| SCHEMBL7161965 | 0.75 | CAMK2A (0.57) | CHRM4CHRM3CLCN2CYP2C9CTSV | |
| SCHEMBL7576547 | 0.74 | CLCN2 (0.55) | CLCN2ATMKDM4EALDH1A1 | |
| SCHEMBL7573910 | 0.74 | ATM (0.46) | ATMKDM4EALDH1A1 | |
| SCHEMBL10439760 | 0.74 | CLCN2 (0.52) | CHRM4CHRM3CLCN2KDM4EALDH1A1 | |
| SCHEMBL10439762 | 0.72 | CLCN2 (0.50) | CHRM4CHRM3CLCN2KDM4EALDH1A1 | |
| SCHEMBL10439653 | 0.72 | CLCN2 (0.42) | CHRM4CHRM3CLCN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |