Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.42 |
| ▸ | PPARA | Q07869 | 9/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406332 | 0.81 | PPARG (0.36) | PPARGPPARAALOX15NPSR1L3MBTL1 | |
| SCHEMBL1805352 | 0.78 | PPARG (0.43) | PPARGPPARAALOX15NPSR1L3MBTL1 | |
| SCHEMBL23754112 | 0.78 | PPARG (0.45) | PPARGPPARAALOX15NPSR1L3MBTL1 | |
| SCHEMBL1960387 | 0.77 | PPARG (0.62) | PPARGPPARANPSR1L3MBTL1MEN1 | |
| SCHEMBL17653510 | 0.77 | PPARG (0.42) | PPARGPPARAALOX15NPSR1L3MBTL1 | |
| SCHEMBL4752621 | 0.77 | PPARG (0.42) | PPARGPPARAALOX15NPSR1L3MBTL1 | |
| SCHEMBL11763480 | 0.77 | PPARG (0.44) | PPARGPPARAALOX15NPSR1L3MBTL1 | |
| SCHEMBL11429585 | 0.76 | HPGD (0.63) | L3MBTL1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29564565 | 0.76 | PPARG (0.41) | PPARGPPARAALOX15NPSR1L3MBTL1 | |
| SCHEMBL3009494 | 0.76 | ALDH1A1 (0.42) | PPARGPPARAALOX15NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381913-A1 | Benzohydroxamic-acid derivatives | SANDOZ AG (CH) | 1990-08-16 | — | — | EP | disclosed |