SCHEMBL1960387

SCHEMBL1960387

CCC(C)(Oc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 13/20 0.62
PPARA Q07869 11/20 0.62
ADORA3 P0DMS8 1/20 0.59
ELANE P08246 1/20 0.44
OPRK1 P41145 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11548490 0.87 ADORA3 (0.61) PPARGPPARAADORA3ELANEOPRK1
SCHEMBL7087893 0.86 PPARG (0.57) PPARGPPARAADORA3ELANEMEN1
SCHEMBL8935669 0.85 ADORA3 (0.60) PPARGPPARAADORA3OPRK1L3MBTL1
SCHEMBL13846158 0.85 ADORA3 (0.60) PPARGPPARAADORA3OPRK1
SCHEMBL5367947 0.85 ADORA3 (0.60) PPARGPPARAADORA3ELANEOPRK1
SCHEMBL5369095 0.85 ADORA3 (0.60) PPARGPPARAADORA3ELANEOPRK1
SCHEMBL5141872 0.85 ADORA3 (0.60) PPARGPPARAADORA3ELANEOPRK1
SCHEMBL8935937 0.85 PPARG (0.53) PPARGPPARAADORA3ELANENPSR1
SCHEMBL82055 0.85 PPARG (0.53) PPARGPPARAADORA3ELANENPSR1
SCHEMBL8935672 0.85 ADORA3 (0.60) PPARGPPARAADORA3OPRK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2507237-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) Dainippon Sumitomo Pharma Co., Ltd. (JP) 2012-10-10 EP claimed
EP-0055357-B1 PROCESS FOR THE PREPARATION OF CHLORINATED PHENOXYALKANOIC ACIDS BASF Aktiengesellschaft (DE) 1984-01-11 EP claimed
EP-4630410-A1 POLQ INHIBITORS Astrazeneca AB (SE) 2025-10-15 EP disclosed
WO-2024121753-A1 POLQ INHIBITORS ASTRAZENECA AB (SE) 2024-06-13 WO disclosed
EP-2507237-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) Dainippon Sumitomo Pharma Co., Ltd. (JP) 2012-10-10 EP disclosed
WO-2011068233-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-06-09 WO disclosed