Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158477 | 0.72 | ALDH1A1 (0.73) | ALDH1A1XDH | |
| SCHEMBL618978 | 0.72 | PNP (0.44) | ALDH1A1PNPXDHMEN1KMT2A | |
| SCHEMBL8356642 | 0.72 | PNP (0.41) | ALDH1A1PNPXDHMEN1KMT2A | |
| SCHEMBL2352519 | 0.71 | PNP (0.43) | ALDH1A1PNPXDHMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28403441 | 0.70 | PNP (0.43) | ALDH1A1PNPMEN1KMT2AGDA | |
| SCHEMBL4560085 | 0.68 | GDA (0.53) | ALDH1A1PNPXDHMEN1KMT2A | |
| SCHEMBL9949248 | 0.68 | PNP (0.41) | ALDH1A1PNPXDHMEN1KMT2A | |
| SCHEMBL28648090 | 0.68 | PNP (0.44) | ALDH1A1PNPXDHMEN1KMT2A | |
| SCHEMBL10998 | 0.68 | GDA (0.53) | ALDH1A1PNPXDHMEN1KMT2A | |
| SCHEMBL133948 | 0.68 | PNP (0.41) | ALDH1A1PNPXDHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386683-A2 | Xanthine derivatives having bronchodilating activity, a process for the preparation thereof and pharmaceutical compositions containing them | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1990-09-12 | — | — | EP | disclosed |