Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441587 | 1.00 | LMNA (0.42) | LMNAGAAALDH1A1VDRHPGD | |
| SCHEMBL10441919 | 0.98 | GAA (0.42) | LMNAGAAALDH1A1VDRHPGD | |
| SCHEMBL31588015 | 0.95 | GAA (0.42) | LMNAGAAALDH1A1VDRHPGD | |
| SCHEMBL23969625 | 0.76 | ALDH1A1 (0.41) | LMNAGAAALDH1A1HPGDKDM4E | |
| SCHEMBL30444783 | 0.76 | ALDH1A1 (0.41) | LMNAGAAALDH1A1HPGDKDM4E | |
| SCHEMBL31572848 | 0.70 | ALDH1A1 (0.41) | GAAALDH1A1VDRHPGDKDM4E | |
| SCHEMBL22033126 | 0.70 | ALDH1A1 (0.39) | GAAALDH1A1VDRHPGDKDM4E | |
| SCHEMBL27048137 | 0.69 | ALDH1A1 (0.41) | LMNAGAAALDH1A1HPGDKDM4E | |
| SCHEMBL12381617 | 0.68 | ALDH1A1 (0.37) | GAAALDH1A1VDRHPGDKDM4E | |
| SCHEMBL22833052 | 0.68 | GAA (0.49) | LMNAGAAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386940-A1 | 6-Beta-(alpha-etherified oxymino)-acyl amino penicillins | BEECHAM GROUP PLC (GB) | 1990-09-12 | — | — | EP | disclosed |