Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.40 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603324 | 0.81 | THRB (0.52) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL10442736 | 0.80 | INPPL1 (0.46) | THRBTHRAINPPL1INPP5AAKT1 | |
| SCHEMBL31473172 | 0.77 | CYP2C9 (0.63) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL31473173 | 0.77 | CYP2C9 (0.63) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL20088746 | 0.77 | CYP2C9 (0.63) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL9717487 | 0.75 | THRB (0.60) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL10405139 | 0.74 | THRB (0.45) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL7307040 | 0.74 | THRB (0.52) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL9718977 | 0.74 | THRB (0.46) | THRBTHRAALDH1A1TSHRRECQL | |
| SCHEMBL9717518 | 0.74 | THRB (0.62) | THRBTHRAALDH1A1TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363688-A1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |