Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444517 | 0.81 | PTGS2 (0.38) | HTR2CHTR2BHTR2ATDP1ALDH1A1 | |
| SCHEMBL10444572 | 0.81 | KCNN4 (0.39) | HTR2CHTR2BTDP1ALDH1A1KDM1A | |
| SCHEMBL3720341 | 0.78 | PTGS2 (0.45) | HTR2CHTR2BHTR2ASLC6A4TDP1 | |
| SCHEMBL8993540 | 0.78 | PTGS2 (0.45) | HTR2CHTR2BHTR2ASLC6A4TDP1 | |
| SCHEMBL11003541 | 0.78 | PTGS2 (0.45) | HTR2CHTR2BHTR2ASLC6A4TDP1 | |
| SCHEMBL9660946 | 0.77 | HTR2C (0.39) | HTR2CHTR2BTDP1GAA | |
| SCHEMBL9660954 | 0.77 | HTR2C (0.39) | HTR2CHTR2BTDP1GAA | |
| SCHEMBL9660957 | 0.77 | HTR2C (0.39) | HTR2CHTR2BTDP1GAA | |
| SCHEMBL10444313 | 0.72 | KCNN4 (0.41) | HTR2CHTR2BTDP1KDM1ARCOR1 | |
| SCHEMBL9725042 | 0.70 | KCNN4 (0.32) | HTR2CHTR2BSLC6A2HTR2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379081-A2 | Process for the preparation of 1-hydroxymethyl oxiranes Z-substituted in position 2 | BASF Aktiengesellschaft (DE) | 1990-07-25 | — | — | EP | disclosed |