Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444313 | 0.91 | KCNN4 (0.41) | KCNN4HTR2CHTR2BTDP1PTGS2 | |
| SCHEMBL10444517 | 0.81 | PTGS2 (0.38) | KCNN4HTR2CHTR2BTDP1PTGS2 | |
| SCHEMBL10444501 | 0.81 | HTR2C (0.36) | HTR2CHTR2BTDP1PTGS2ALDH1A1 | |
| SCHEMBL9660954 | 0.80 | HTR2C (0.39) | HTR2CHTR2BTDP1GAAPOLB | |
| SCHEMBL9660957 | 0.80 | HTR2C (0.39) | HTR2CHTR2BTDP1GAAPOLB | |
| SCHEMBL9660946 | 0.80 | HTR2C (0.39) | HTR2CHTR2BTDP1GAAPOLB | |
| SCHEMBL11003541 | 0.78 | PTGS2 (0.45) | HTR2CHTR2BTDP1PTGS2ALDH1A1 | |
| SCHEMBL8993540 | 0.78 | PTGS2 (0.45) | HTR2CHTR2BTDP1PTGS2ALDH1A1 | |
| SCHEMBL3720341 | 0.78 | PTGS2 (0.45) | HTR2CHTR2BTDP1PTGS2ALDH1A1 | |
| SCHEMBL9725042 | 0.76 | KCNN4 (0.32) | KCNN4HTR2CHTR2BTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379081-A2 | Process for the preparation of 1-hydroxymethyl oxiranes Z-substituted in position 2 | BASF Aktiengesellschaft (DE) | 1990-07-25 | — | — | EP | disclosed |