Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055348 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NAAAMEN1KMT2ATSHR | |
| SCHEMBL921655 | 0.98 | SIGMAR1 (0.39) | SIGMAR1NAAAMEN1KMT2ATSHR | |
| SCHEMBL3326401 | 0.95 | SIGMAR1 (0.46) | SIGMAR1NAAAMEN1KMT2ATSHR | |
| SCHEMBL9214648 | 0.93 | SIGMAR1 (0.49) | SIGMAR1NAAAMEN1KMT2AEPHX1 | |
| SCHEMBL10444336 | 0.93 | SIGMAR1 (0.49) | SIGMAR1NAAAMEN1KMT2AEPHX1 | |
| SCHEMBL10501805 | 0.93 | SIGMAR1 (0.49) | SIGMAR1NAAAMEN1KMT2AEPHX1 | |
| SCHEMBL9737302 | 0.93 | SIGMAR1 (0.49) | SIGMAR1NAAAMEN1KMT2AEPHX1 | |
| SCHEMBL6380675 | 0.93 | SIGMAR1 (0.43) | SIGMAR1NAAAMEN1KMT2ATSHR | |
| SCHEMBL7054446 | 0.91 | SIGMAR1 (0.46) | SIGMAR1NAAAEPHX1CYP1A2 | |
| SCHEMBL194144 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |