Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444336 | 1.00 | SIGMAR1 (0.49) | SIGMAR1CYP1A2NAAAEPHX1EPHX2 | |
| SCHEMBL10501805 | 1.00 | SIGMAR1 (0.49) | SIGMAR1CYP1A2NAAAEPHX1EPHX2 | |
| SCHEMBL9214648 | 1.00 | SIGMAR1 (0.49) | SIGMAR1CYP1A2NAAAEPHX1EPHX2 | |
| SCHEMBL7054446 | 0.98 | SIGMAR1 (0.46) | SIGMAR1CYP1A2NAAAEPHX1EPHX2 | |
| SCHEMBL3326401 | 0.98 | SIGMAR1 (0.46) | SIGMAR1CYP1A2NAAAEPHX1EPHX2 | |
| SCHEMBL6380675 | 0.96 | SIGMAR1 (0.43) | SIGMAR1CYP1A2NAAAEPHX1EPHX2 | |
| SCHEMBL10444597 | 0.93 | SIGMAR1 (0.42) | SIGMAR1CYP1A2NAAAEPHX1MEN1 | |
| SCHEMBL7055348 | 0.93 | SIGMAR1 (0.42) | SIGMAR1CYP1A2NAAAEPHX1MEN1 | |
| SCHEMBL303718 | 0.91 | CYP1A2 (0.44) | SIGMAR1CYP1A2NAAAEPHX1EPHX2 | |
| SCHEMBL921655 | 0.91 | SIGMAR1 (0.39) | SIGMAR1CYP1A2NAAAEPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |