SCHEMBL1044537

SCHEMBL1044537

O=C(O)C1C=CCC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25992990 0.82 EGLN1 (0.37)
SCHEMBL2501121 0.79
SCHEMBL20029139 0.78
SCHEMBL1226420 0.77 POLB (0.47)
SCHEMBL4104220 0.77
SCHEMBL16349268 0.71
Bicarbonate SCHEMBL6454693 0.69
SCHEMBL25992987 0.69 POLB (0.35)
SCHEMBL5342543 0.69 CHRNB2 (0.33)
SCHEMBL25992984 0.69 ABAT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109957146-B Preparation method of modified alumina particles used as nucleating agent 中国石油天然气股份有限公司 2021-01-29 CN claimed
US-20100168344-A1 POLYESTER BASED BLEND AND PACKAGING ARTICLE MADE THEREFROM FAR EASTERN NEW CENTURY CORPORATION (TW) 2010-07-01 US claimed
EP-1076636-B1 METHOD FOR PRODUCING SUBSTITUTED BENZENES BAYER CROPSCIENCE AG (DE) 2003-07-09 EP claimed
US-4229367-A Preparation of trans-4-alkyl-cyanoarylcyclohexanes SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-10-21 US claimed
US-12421178-B2 Non-cryogenic, ammonia-free reduction of aryl compounds University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-09-23 US disclosed
EP-4603469-A1 METHOD FOR REDUCTION OF ORGANIC COMPOUNDS WITH MECHANOCHEMICAL TREATMENT Tallinn University of Technology (EE) 2025-08-20 EP disclosed
US-20240425997-A1 REACTOR AND OPERATING METHOD UNIVERSITEIT TWENTE (NL) 2024-12-26 US disclosed
CN-118955260-A Synthesis method for converting pyridine into aromatic dialdehyde 四川大学 2024-11-15 CN disclosed
WO-2024210060-A1 REDUCTION METHOD 国立大学法人北海道大学 2024-10-10 WO disclosed
US-20240092708-A1 Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2024-03-21 US disclosed
US-11866386-B2 Non-cryogenic, ammonia-free reduction of aryl compounds University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-01-09 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-6750251-B2 TO PRODUCE MEDICAMENT FOR THERAPY AND PROPHYLAXIS OF CANCER THE UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (UK) (GB) 2004-06-15 US disclosed
EP-1076636-B1 METHOD FOR PRODUCING SUBSTITUTED BENZENES BAYER CROPSCIENCE AG (DE) 2003-07-09 EP disclosed
US-20030023088-A1 Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (UK), THE (GB) 2003-01-30 US disclosed
CN-1323242-A Hydroformylation process using chlorophosphite-metal catalyst system EASTMAN CHEM CO (US) 2001-11-21 CN disclosed
EP-1076636-A1 METHOD FOR PRODUCING SUBSTITUTED BENZENES BAYER AG (DE) 2001-02-21 EP disclosed
WO-1999057084-A1 METHOD FOR PRODUCING SUBSTITUTED BENZENES BAYER AKTIENGESELLSCHAFT (DE) 1999-11-11 WO disclosed
US-4229367-A Preparation of trans-4-alkyl-cyanoarylcyclohexanes SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-10-21 US disclosed
US-4187316-A ENZYME INHIBITORS MERRELL TORAUDE ET COMPAGNIE (FR) 1980-02-05 US disclosed