Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPR1 | P16066 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043068 | 0.78 | LTA4H (0.45) | CA2CYP19A1FFAR1DRD2DRD3 | |
| SCHEMBL1044542 | 0.78 | PBRM1 (0.50) | BLMLMNAMAPTHTTAHR | |
| SCHEMBL1877574 | 0.78 | CA2 (0.48) | AHRCA2CYP19A1FFAR1DRD2 | |
| SCHEMBL1042715 | 0.78 | LTA4H (0.45) | CA2CYP19A1FFAR1DRD2DRD3 | |
| SCHEMBL1879364 | 0.78 | CYP3A4 (0.52) | DRD2DRD3MAOBCYP3A4 | |
| SCHEMBL16656033 | 0.78 | PBRM1 (0.50) | BLMLMNAMAPTHTTAHR | |
| SCHEMBL15864958 | 0.76 | CA2 (0.54) | BLMLMNAMAPTHTTAHR | |
| SCHEMBL15864961 | 0.76 | CA2 (0.54) | BLMLMNAMAPTHTTAHR | |
| SCHEMBL20612385 | 0.76 | RPS6KB2 (0.46) | BLMLMNAMAPTHTTCA2 | |
| SCHEMBL1079302 | 0.74 | NISCH (0.48) | LMNAMAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271635-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009133109-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2009-11-05 | — | — | WO | disclosed |