Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10446089 | 0.93 | GFER (0.49) | GFERAXLPTGS1PTGS2NPC1 | |
| SCHEMBL9269941 | 0.79 | PDE4B (0.42) | GFERAXLPTGS1PTGS2NPC1 | |
| SCHEMBL9269933 | 0.79 | PDE4B (0.42) | GFERAXLPTGS1PTGS2NPC1 | |
| SCHEMBL9167195 | 0.78 | PTGS1 (0.64) | PTGS1PTGS2NPC1RAB9AALDH1A1 | |
| SCHEMBL10445851 | 0.77 | TSHR (0.37) | PTGS1PTGS2NPC1RAB9AMAPT | |
| SCHEMBL9262517 | 0.77 | PDE4B (0.40) | GFERAXLPTGS1PTGS2NPC1 | |
| SCHEMBL9262523 | 0.77 | PDE4B (0.40) | GFERAXLPTGS1PTGS2NPC1 | |
| SCHEMBL9262520 | 0.77 | PDE4B (0.40) | GFERAXLPTGS1PTGS2NPC1 | |
| SCHEMBL9852614 | 0.77 | GFER (0.47) | GFERAXLPTGS1PTGS2NPC1 | |
| SCHEMBL28282484 | 0.74 | PTGS1 (0.58) | PTGS1PTGS2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373461-A2 | Benzazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-06-20 | — | — | EP | disclosed |