Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445819 | 0.93 | GFER (0.47) | GFERAXLPTGS1PTGS2MAPT | |
| SCHEMBL9852614 | 0.78 | GFER (0.47) | GFERAXLPTGS1PTGS2MAPT | |
| SCHEMBL10158221 | 0.78 | PTGS1 (0.61) | PTGS1PTGS2MAPTALDH1A1MEN1 | |
| SCHEMBL10445813 | 0.77 | TP53 (0.35) | PTGS1PTGS2MAPTALDH1A1LMNA | |
| SCHEMBL9269933 | 0.75 | PDE4B (0.42) | GFERAXLPTGS1PTGS2MAPT | |
| SCHEMBL9269941 | 0.75 | PDE4B (0.42) | GFERAXLPTGS1PTGS2MAPT | |
| SCHEMBL9262520 | 0.73 | PDE4B (0.40) | GFERAXLPTGS1PTGS2MAPT | |
| SCHEMBL9262517 | 0.73 | PDE4B (0.40) | GFERAXLPTGS1PTGS2MAPT | |
| SCHEMBL9262523 | 0.73 | PDE4B (0.40) | GFERAXLPTGS1PTGS2MAPT | |
| SCHEMBL6630285 | 0.72 | NPC1 (0.63) | GFERAXLMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373461-A2 | Benzazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-06-20 | — | — | EP | disclosed |