Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL888281 | 0.99 | DGKA (0.49) | DGKADNM1PRKCAPAMKDM4E | |
| Hydrochloric Acid SCHEMBL18209372 | 0.99 | DGKA (0.49) | DGKADNM1PRKCAPAMKDM4E | |
| SCHEMBL441411 | 0.93 | MGLL (0.51) | DGKAPRKCAMGLLMAPTEPHX2 | |
| SCHEMBL747314 | 0.93 | MGLL (0.51) | DGKAPRKCAMGLLMAPTEPHX2 | |
| Hydrochloric Acid SCHEMBL1047267 | 0.92 | MGLL (0.50) | DGKAPRKCAMGLLMAPTEPHX2 | |
| Hydrochloric Acid SCHEMBL421821 | 0.92 | MGLL (0.50) | DGKAPRKCAMGLLMAPTEPHX2 | |
| Water SCHEMBL6549699 | 0.92 | MGLL (0.50) | DGKAPRKCAMGLLMAPTEPHX2 | |
| SCHEMBL22400859 | 0.88 | DGKA (0.51) | DGKADNM1PRKCAPAMKDM4E | |
| Hydrochloric Acid SCHEMBL21328518 | 0.87 | DGKA (0.50) | DGKADNM1PRKCAPAMLMNA | |
| Hydrochloric Acid SCHEMBL21293922 | 0.87 | DGKA (0.50) | DGKADNM1PRKCAPAMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397244-B1 | TREATMENT OF BREAST CANCER USING A COMBINATION OF A CATIONIC LIPOSOMAL FORMULATION OF TAXANE, A NON-LIPOSOMAL FORMULATION OF TAXANE AND A FURTHER ACTIVE AGENT | SYNCORE BIOTECHNOLOGY CO LTD (TW) | 2021-10-06 | — | — | EP | claimed |
| EP-3939572-B1 | VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS | UNIV YALE (US) | 2024-03-27 | — | — | EP | disclosed |
| EP-3520780-B1 | VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS | UNIV YALE (US) | 2023-07-26 | — | — | EP | disclosed |
| EP-3939572-A1 | VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS | Yale University, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| EP-3520780-A1 | VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS | Yale University (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-2836234-B1 | VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS | UNIV YALE (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-2286795-A1 | Method of producing a cationic liposomal preparation comprising a lipophilic compound | MediGene AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| EP-2277507-A1 | Method of producing a cationic liposomal preparation comprising a lipophilic compound | MediGene AG (DE) | 2011-01-26 | — | — | EP | disclosed |
| EP-2200637-A2 | LONG INTERSPERSED NUCLEAR ELEMENT POLYPEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF | The J. David Gladstone Institutes (US) | 2010-06-30 | — | — | EP | disclosed |
| EP-2108362-A2 | Method of producing a cationic liposomal preparation comprising a lipophilic compound | Medigene AG (DE) | 2009-10-14 | — | — | EP | disclosed |
| EP-1530465-B1 | METHOD OF PRODUCING A CATIONIC LIPOSOMAL PREPARATION COMPRISING A LIPOPHILIC COMPOUND | MEDIGENE AG (DE) | 2009-09-30 | — | — | EP | disclosed |
| WO-2009038756-A2 | LONG INTERSPERSED NUCLEAR ELEMENT POLYPEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF | THE J. DAVID GLADSTONE INSTITUTES (US) | 2009-03-26 | — | — | WO | disclosed |
| EP-1767192-A2 | Cationic lipid compositions targeting angiogenic endothelial cells | The Regents of the University of California (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1014945-A1 | CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS | The Regents of the University of California (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998040052-A9 | CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS | UNIV CALIFORNIA (US) | 1999-09-02 | — | — | WO | disclosed |
| WO-1998040052-A1 | CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-09-17 | — | — | WO | disclosed |