Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731676 | 0.76 | NOTUM (0.44) | POLBRECQLKMT2A | |
| SCHEMBL9731353 | 0.75 | CA1 (0.43) | — | |
| SCHEMBL9731532 | 0.74 | STS (0.42) | — | |
| SCHEMBL10445910 | 0.73 | ACACB (0.36) | POLBKMT2A | |
| SCHEMBL20040955 | 0.73 | NR2E1 (0.42) | DPP4NR2E1MEN1POLBRECQL | |
| SCHEMBL10445947 | 0.73 | FFAR4 (0.34) | ADRB1 | |
| SCHEMBL10446268 | 0.72 | STS (0.38) | — | |
| SCHEMBL25745866 | 0.67 | ADRB1 (0.46) | DPP4ADRB1ARCCR2 | |
| SCHEMBL2252772 | 0.65 | ADRB1 (0.60) | DPP4ADRB1 | |
| SCHEMBL25745795 | 0.63 | FFAR4 (0.45) | DPP4ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397602-A1 | N-phenylpyrrolidines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | claimed |
| EP-0397602-A1 | N-phenylpyrrolidines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | disclosed |