SCHEMBL10446296

SCHEMBL10446296

CC1=CC(=O)C(C(C)(C)C(O)O)=CC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.41
PLK1 P53350 1/20 0.41
PLK2 Q9NYY3 1/20 0.41
STAT3 P40763 1/20 0.34
MEN1 O00255 1/20 0.31
PLIN1 O60240 1/20 0.31
NR1I2 O75469 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GSR P00390 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
GAA P10253 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
HSPD1 P10809 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552489 0.76 MAPT (0.43) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL11247339 0.73 STAT3 (0.39) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL30770580 0.71 STAT3 (0.41) EEF2KPLK1PLK2STAT3LMNA
SCHEMBL11277727 0.69 MEN1 (0.49) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL30770698 0.69 STAT3 (0.39) EEF2KPLK1PLK2STAT3
P-Xyloquinone SCHEMBL49964 0.69 PLK1 (0.60) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL10447078 0.64 PLK1 (0.68) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL49783 0.62 MAPT (0.50) MEN1ALDH1A1LMNAGAAMAPT
SCHEMBL7946964 0.61 PLK1 (0.46) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL11237495 0.61 PLK1 (0.63) EEF2KPLK1PLK2STAT3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383536-A2 Thermo-sensitive transfer printing medium SEIKO INSTRUMENTS INC. (JP) 1990-08-22 EP disclosed