Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PYGM | P11217 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 5/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404902 | 0.91 | POLB (0.42) | POLBTDP1KDM4ENPC1CYP2C9 | |
| SCHEMBL301772 | 0.91 | POLB (0.42) | POLBTDP1KDM4ENPC1CYP2C9 | |
| SCHEMBL422032 | 0.90 | POLB (0.57) | HPSEPOLBTDP1DUSP3PTPN5 | |
| SCHEMBL24204893 | 0.88 | POLB (0.41) | HPSEPOLBTDP1DUSP3PTPN5 | |
| SCHEMBL716921 | 0.87 | PYGL (0.53) | HPSEPOLBTDP1PYGMKDM4E | |
| SCHEMBL29404149 | 0.87 | PYGL (0.53) | HPSEPOLBTDP1PYGMKDM4E | |
| SCHEMBL3417323 | 0.86 | TDP1 (0.54) | HPSEPOLBTDP1DUSP3PTPN5 | |
| SCHEMBL29401261 | 0.85 | POLB (0.58) | HPSEPOLBTDP1DUSP3PTPN5 | |
| SCHEMBL260857 | 0.85 | POLB (0.58) | HPSEPOLBTDP1DUSP3PTPN5 | |
| SCHEMBL8906676 | 0.84 | POLB (0.55) | HPSEPOLBTDP1DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649040-B2 | Thermoplastic resin comprisingpolyimide, polysulfone or blend; glass fiber, carbon fiber or ceramic fiber; and perfluorobutyl potassium sulfonate, potassium sulfone sulfonate or sodium dodecylpenzenesulfonate; melt processability; bromine- and chlorine-free | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-01-19 | — | — | US | claimed |
| US-7411014-B2 | Stabilization of polyetherimide sulfones | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-08-12 | — | — | US | claimed |
| US-20070179234-A1 | FLAME RETARDANT FIBER REINFORCED COMPOSITION WITH IMPROVED FLOW | GENERAL ELECTRIC COMPANY (US) | 2007-08-02 | — | — | US | claimed |
| EP-1318174-B1 | Method of manufacture of polyester molding compositions and articles produced therefrom | GEN ELECTRIC (US) | 2007-03-07 | — | — | EP | claimed |
| JP-2007502347-A | — | — | 2007-02-08 | — | — | JP | claimed |
| US-20060281840-A1 | Stabilization of polyetherimide sulfones | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2006-12-14 | — | — | US | claimed |
| US-7147906-B2 | Data storage medium comprising polyimides | GENERAL ELECTRIC COMPANY (US) | 2006-12-12 | — | — | US | claimed |
| EP-1664196-A2 | FLAME RETARDANT FIBER REINFORCED COMPOSITION WITH IMPROVED FLOW | GENERAL ELECTRIC COMPANY (US) | 2006-06-07 | — | — | EP | claimed |
| US-7041773-B2 | Polyimide sulfones, method and articles made therefrom | GENERAL ELECTRIC COMPANY (US) | 2006-05-09 | — | — | US | claimed |
| US-20060084748-A1 | Flame retardant fiber reinforced composition with improved flow | CITIBANK, N.A., AS COLLATERAL AGENT | 2006-04-20 | — | — | US | claimed |
| EP-1633802-A1 | BENZIMIDAZOLE DIAMINE-BASED POLYETHERIMIDE COMPOSITIONS AND METHODS FOR MAKING THEM | GENERAL ELECTRIC COMPANY (US) | 2006-03-15 | — | — | EP | claimed |
| US-20050070684-A1 | Polyimide sulfones, method and articles made therefrom | GENERAL ELECTRIC COMPANY | 2005-03-31 | — | — | US | claimed |
| US-20050048299-A1 | Polyimide, polysulfone, fibrous reinforcement (fiber glass, carbon fiber and ceramic fiber), and sulfonate salt; improved melt processability | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2005-03-03 | — | — | US | claimed |
| WO-2005017043-A2 | FLAME RETARDANT FIBER REINFORCED COMPOSITION WITH IMPROVED FLOW | GENERAL ELECTRIC COMPANY (US) | 2005-02-24 | — | — | WO | claimed |
| US-20050038145-A1 | Flame retardant fiber reinforced composition with improved flow | GENERAL ELECTRIC COMPANY | 2005-02-17 | — | — | US | claimed |
| WO-2005005515-A1 | DATA STORAGE MEDIUM COMPRISING POLYIMIDES | GENERAL ELECTRIC COMPANY (US) | 2005-01-20 | — | — | WO | claimed |
| US-20040265605-A1 | Data storage medium comprising polyimides | GENERAL ELECTRIC COMPANY | 2004-12-30 | — | — | US | claimed |
| WO-2004108797-A1 | BENZIMIDAZOLE DIAMINE-BASED POLYETHERIMIDE COMPOSITIONS AND METHODS FOR MAKING THEM | GENERAL ELECTRIC COMPANY (US) | 2004-12-16 | — | — | WO | claimed |
| US-20040249117-A1 | Benzimidazole diamine-based polyetherimide compositions and methods for making them | GENERAL ELECTRIC COMPANY | 2004-12-09 | — | — | US | claimed |
| US-3989670-A | Method for making polyetherimides | GENERAL ELECTRIC COMPANY (US) | 1976-11-02 | — | — | US | claimed |