Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251250 | 0.80 | HTR2A (0.43) | KDM1AMAOBHTR2ARETIDO1 | |
| Hydrochloric Acid SCHEMBL9296485 | 0.79 | HTR2A (0.45) | KDM1AMAOBHTR2ARETIDO1 | |
| SCHEMBL16594106 | 0.79 | KDM1A (0.40) | KDM1AMAOBHTR2ARETIDO1 | |
| SCHEMBL9527857 | 0.67 | ALDH1A1 (0.36) | HTR2AACP3DRD2HTR2CHTR2B | |
| SCHEMBL440138 | 0.67 | HTR2A (0.54) | HTR2ARETIDO1ACP3 | |
| SCHEMBL29793145 | 0.67 | HTR2A (0.54) | HTR2ARETIDO1ACP3 | |
| SCHEMBL9177026 | 0.67 | HTR2A (0.41) | KDM1AMAOBHTR2ARETIDO1 | |
| SCHEMBL30094172 | 0.66 | IDO1 (0.50) | HTR2ARETIDO1HTR6SIGMAR1 | |
| SCHEMBL1117278 | 0.66 | IDO1 (0.50) | HTR2ARETIDO1HTR6SIGMAR1 | |
| SCHEMBL788818 | 0.63 | KDM1A (0.50) | KDM1AMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381902-A1 | Tetralin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-08-16 | — | — | EP | disclosed |