Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 11/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499 | 0.88 | PIK3CG (0.44) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL10361 | 0.87 | PIK3CG (0.49) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL12710083 | 0.81 | ABL1 (0.50) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL10369 | 0.77 | CYP1A2 (0.56) | PIK3CGPIK3CA | |
| SCHEMBL10338 | 0.74 | PIK3CG (0.55) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL10392 | 0.71 | PIK3CG (0.51) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL10456 | 0.71 | PIK3CG (0.51) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL12710081 | 0.69 | ABL1 (0.49) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL10110 | 0.69 | PIK3CG (0.47) | PIK3CGPIK3CAPIK3CD | |
| SCHEMBL16448998 | 0.68 | KMT2A (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041634-A1 | PYRAZOLE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-04-07 | — | — | WO | disclosed |