Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19591887 | 0.89 | KMT2A (0.73) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL25030583 | 0.88 | KMT2A (0.67) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6518512 | 0.87 | KMT2A (0.67) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4189064 | 0.86 | KMT2A (0.64) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6521265 | 0.86 | KMT2A (0.65) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL1116738 | 0.85 | KMT2A (0.76) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL29634495 | 0.85 | KMT2A (0.76) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL2497123 | 0.85 | THRB (0.68) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL10331458 | 0.85 | KMT2A (0.64) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6523383 | 0.83 | KMT2A (0.62) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952150-B2 | Prostaglandin transporter inhibitors and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |