SCHEMBL10447189

SCHEMBL10447189

CCCCCCCCOC1(Br)C=CC(c2ccccc2F)=CC1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MEN1 O00255 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PDK2 Q15119 2/20 0.32
FAAH O00519 7/20 0.32
MGLL Q99685 1/20 0.32
TLR8 Q9NR97 1/20 0.31
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28005983 0.86 L3MBTL1 (0.36) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL27696494 0.83 NR5A1 (0.38) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL10595491 0.83 NR5A1 (0.38) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL10598620 0.83 NR5A1 (0.38) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL7201534 0.82 NR5A1 (0.36) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL9225241 0.80 PDK2 (0.34) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL9223753 0.80 PDK2 (0.34) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL9228706 0.80 PDK2 (0.34) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL9219071 0.80 PDK2 (0.34) L3MBTL1CYP2C9CYP2C19MEN1RECQL
SCHEMBL9223531 0.80 PDK2 (0.34) L3MBTL1CYP2C9CYP2C19MEN1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0360043-A1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed