Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219071 | 1.00 | PDK2 (0.34) | PDK2CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL9228706 | 1.00 | PDK2 (0.34) | PDK2CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL9223531 | 1.00 | PDK2 (0.34) | PDK2CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL9225241 | 1.00 | PDK2 (0.34) | PDK2CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL9227211 | 0.99 | PDK2 (0.33) | PDK2CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL9225218 | 0.96 | PDK2 (0.32) | PDK2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL9223485 | 0.91 | — | — | |
| SCHEMBL28005983 | 0.91 | L3MBTL1 (0.36) | PDK2CYP2C9CYP2C19MEN1RECQL | |
| SCHEMBL9221755 | 0.87 | KDM4E (0.30) | — | |
| SCHEMBL9225848 | 0.81 | HSD11B1 (0.31) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-B1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK PATENT GMBH (DE) | 1995-12-20 | — | — | EP | disclosed |
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |