Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15735798 | 0.82 | ALDH1A1 (0.39) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL15735800 | 0.82 | ALDH1A1 (0.39) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL13637136 | 0.81 | ALDH1A1 (0.43) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL13315032 | 0.72 | ALDH1A1 (0.41) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL3488211 | 0.72 | CA2 (0.39) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL18817541 | 0.72 | CA2 (0.50) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL7154999 | 0.72 | CA2 (0.50) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL3543202 | 0.71 | ALDH1A1 (0.45) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL12349246 | 0.70 | GAA (0.45) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL9736281 | 0.70 | PIK3CD (0.34) | CA2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350211-A2 | Novel 6-amido-1-methyl carbapenems | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |