SCHEMBL10447306

SCHEMBL10447306

C=Cc1cccc(C(=C)C(=O)O)c1Br

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
KDM4E B2RXH2 2/20 0.31
TAS2R14 Q9NYV8 1/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
HSP90AA1 P07900 1/20 0.31
ATM Q13315 1/20 0.31
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828320 0.84 ALDH1A1 (0.43) CA12CA1CA2CA9KDM4E
SCHEMBL9027781 0.82 CA1 (0.39) CA12CA1CA2CA9KDM4E
SCHEMBL372707 0.78 PRNP (0.40) ALDH1A1LMNAMEN1KMT2AALOX15
SCHEMBL29403670 0.78 AKR1C3 (0.47) ALDH1A1MAPTHSP90AA1ATM
SCHEMBL6828127 0.75 LMNA (0.44) CA12CA1CA2CA9KDM4E
SCHEMBL16952259 0.74 ALDH1A1 (0.34) ALDH1A1
SCHEMBL16961865 0.72 ALDH1A1 (0.46) ALDH1A1LMNAMEN1KMT2A
SCHEMBL21668675 0.71 ALDH1A1 (0.41) CA12CA1CA2CA9KDM4E
SCHEMBL16953214 0.71 ALDH1A1 (0.32) ALDH1A1
SCHEMBL29003971 0.71 LMNA (0.46) CYP1A2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364785-A1 Thermosetting resin composition, printed circuit board using the resin composition and process for producing printed circuit board HITACHI, LTD. (JP) 1990-04-25 EP disclosed