SCHEMBL10447368

SCHEMBL10447368

CCC(C)(C)C(=O)Nc1ccc(O)c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.55
IDO1 P14902 10/20 0.53
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.50
RIPK1 Q13546 1/20 0.49
KAT2B Q92831 1/20 0.46
KAT8 Q9H7Z6 1/20 0.46
CHEK1 O14757 1/20 0.44
PIM1 P11309 1/20 0.44
LTK P29376 1/20 0.44
LIMK1 P53667 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
HSP90AA1 P07900 1/20 0.44
PSD A5PKW4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064143 0.91 LMNA (0.57) EP300IDO1LMNAPOLBRIPK1
SCHEMBL20306580 0.84 IDO1 (0.59) EP300IDO1KAT2BKAT8HSP90AA1
SCHEMBL10027976 0.81 LMNA (0.59) LMNAPOLBRIPK1
SCHEMBL16300542 0.80 POLB (0.58) LMNAPOLBRIPK1
SCHEMBL12863541 0.80 POLB (0.58) LMNAPOLBRIPK1
SCHEMBL17617963 0.78 LMNA (0.60) LMNAPOLBRIPK1
SCHEMBL16256513 0.78 POLB (0.56) LMNAPOLBRIPK1
SCHEMBL25631119 0.75 CDC25B (0.50) LMNAPOLBRIPK1
SCHEMBL590479 0.75 RXFP1 (0.66) EP300IDO1POLBKAT2BKAT8
SCHEMBL12863534 0.75 POLB (0.56) LMNAPOLBRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170045818-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION FOR LITHOGRAPHY CONTAINING POLYMER HAVING BLOCKED ISOCYANATE STRUCTURE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-02-16 US disclosed
US-20170045819-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION FOR LITHOGRAPHY CONTAINING POLYMER HAVING ACRYLAMIDE STRUCTURE AND ACRYLIC ACID ESTER STRUCTURE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-02-16 US disclosed
US-9285679-B2 Actinic ray-sensitive or radiation-sensitive composition, and resist film, resist-coated mask blanks, resist pattern forming method and photomask each using the composition FUJIFILM CORPORATION (JP) 2016-03-15 US disclosed
US-9029064-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-12 US disclosed
US-20150010855-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, AND RESIST FILM, RESIST-COATED MASK BLANKS, RESIST PATTERN FORMING METHOD AND PHOTOMASK EACH USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2015-01-08 US disclosed
US-8492078-B2 Patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-8440386-B2 Patterning process, resist composition, and acetal compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-14 US disclosed
US-20120183903-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-07-19 US disclosed
US-20110236826-A1 PATTERNING PROCESS, RESIST COMPOSITION, AND ACETAL COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-09-29 US disclosed
US-20110177462-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110236826-A1 PATTERNING PROCESS, RESIST COMPOSITION, AND ACETAL COMPOUND PARG, RAD51, CD38 EP300 528/4885IDO1 4089/4885LMNA 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.