SCHEMBL10027976

SCHEMBL10027976

CCC(C)(C)C(=O)Nc1ccccc1O

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
POLB P06746 1/20 0.59
GAA P10253 6/20 0.50
HTT P42858 4/20 0.50
RIPK1 Q13546 4/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NPC1 O15118 2/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
ALDH1A1 P00352 1/20 0.46
THRB P10828 1/20 0.46
KDM1A O60341 1/20 0.44
RAB9A P51151 1/20 0.44
MEN1 O00255 1/20 0.44
CETP P11597 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064143 0.84 LMNA (0.57) LMNAPOLBGAAHTTRIPK1
SCHEMBL8243174 0.82 CETP (0.62) LMNAGAAHTTMAPTKMT2A
SCHEMBL12963094 0.81 LMNA (0.57) LMNAPOLBGAAHTTRIPK1
SCHEMBL7207413 0.81 LMNA (0.61) LMNAPOLBGAAHTTRIPK1
SCHEMBL19422611 0.81 POLB (0.57) LMNAPOLBGAAHTTRIPK1
SCHEMBL10447368 0.81 EP300 (0.55) LMNAPOLBRIPK1
SCHEMBL14483803 0.81 CA1 (0.59) LMNAPOLB
SCHEMBL5879414 0.81 LMNA (0.65) LMNAPOLBGAAHTTRIPK1
SCHEMBL1555152 0.80 GAA (0.54) LMNAGAAHTTMAPTKMT2A
SCHEMBL28741300 0.80 LMNA (0.56) LMNAPOLBGAAHTTRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230194986-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-22 US disclosed
US-9519213-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-12-13 US disclosed
US-20140255843-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-11 US disclosed
US-20120021357-A1 POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME NEC CORPORATION (JP) 2012-01-26 US disclosed
US-20110281217-A1 NEGATIVE PHOTOSENSITIVE INSULATING RESIN COMPOSITION AND METHOD FOR PATTERNING USING THE SAME NEC CORPORATION (JP) 2011-11-17 US disclosed
US-7939241-B2 (Meth)acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2011-05-10 US disclosed
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2009-03-12 US disclosed
US-20080241752-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20070041698-A1 Photosensitive resin composition for forming optical waveguide, optical waveguide, and method for forming optical waveguide pattern NEC CORPORATION (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method MMAB, DNMT3A, MAT1A LMNA 4190/4885POLB 672/4885GAA 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.