Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | DRD3 | P35462 | 8/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776784 | 0.91 | DRD2 (0.63) | HTR1ADRD2DRD3DRD4MEN1 | |
| Bromide SCHEMBL10975000 | 0.90 | DRD2 (0.64) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL9776909 | 0.88 | DRD2 (0.54) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL7503050 | 0.86 | DRD3 (0.60) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL10447452 | 0.84 | DRD2 (0.56) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL10447705 | 0.83 | DRD3 (0.60) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL9776892 | 0.81 | DRD2 (0.49) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL10447122 | 0.81 | DRD3 (0.62) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL9776884 | 0.80 | DRD3 (0.54) | HTR1ADRD2DRD3DRD4MEN1 | |
| SCHEMBL10447757 | 0.77 | DRD2 (0.54) | HTR1ADRD2DRD3DRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361300-A1 | Use of 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as drugs, 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as well as processes for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1990-04-04 | — | — | EP | disclosed |