Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.60 |
| ▸ | DRD2 | P14416 | 10/20 | 0.60 |
| ▸ | DRD4 | P21917 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776884 | 0.93 | DRD3 (0.54) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL9776784 | 0.88 | DRD2 (0.63) | DRD3DRD2DRD4MEN1KMT2A | |
| Bromide SCHEMBL10975000 | 0.87 | DRD2 (0.64) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL9776909 | 0.86 | DRD2 (0.54) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL7503050 | 0.84 | DRD3 (0.60) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL10447679 | 0.83 | HTR1A (0.54) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL9776845 | 0.82 | DRD2 (0.50) | DRD3DRD2DRD4 | |
| SCHEMBL10447452 | 0.81 | DRD2 (0.56) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL7329629 | 0.81 | DRD2 (0.60) | DRD3DRD2DRD4CYP2D6LMNA | |
| SCHEMBL7330663 | 0.81 | DRD2 (0.60) | DRD3DRD2DRD4CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361300-A1 | Use of 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as drugs, 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as well as processes for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1990-04-04 | — | — | EP | disclosed |