Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | TPMT | P51580 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SELL | P14151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761236 | 0.94 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28224396 | 0.85 | CA12 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28002197 | 0.83 | HCAR1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12269291 | 0.83 | KDM4E (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8012164 | 0.83 | POLB (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11954958 | 0.83 | TPMT (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12837657 | 0.83 | TPMT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8015706 | 0.79 | UNG (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12260650 | 0.78 | ALDH1A1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8006121 | 0.78 | KDM4E (0.50) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222456-B2 | Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-07-17 | — | — | US | disclosed |