SCHEMBL10447993

SCHEMBL10447993

CCOC(=O)CC(c1ccc(O)c(C(C)(C)C)c1)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.43
GAA P10253 1/20 0.43
XBP1 P17861 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HTT P42858 2/20 0.38
CYP2C9 P11712 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 2/20 0.38
NR1I2 O75469 1/20 0.38
MIF P14174 1/20 0.38
TYR P14679 1/20 0.38
ALOX15 P16050 1/20 0.38
NFE2L2 Q16236 1/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9239126 0.88 ATM (0.39) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL6909559 0.88 PDE5A (0.37) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL21629685 0.86 ALDH1A1 (0.41) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL5617864 0.86 GAA (0.46) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28729927 0.86 GAA (0.46) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL10276510 0.82 ALDH1A1 (0.38) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28311334 0.82 ALDH1A1 (0.43) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL7108338 0.82 ALDH1A1 (0.43) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28287386 0.81 ALDH1A1 (0.42) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL6227382 0.81 GAA (0.39) ATMGAAXBP1NPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392392-A1 Method for stabilizing polyolefins CIBA-GEIGY AG (CH) 1990-10-17 EP claimed
CN-1038595-C Process for stabilising polyolefine CIBA GEIGY AG (CH) 1998-06-03 CN disclosed
CN-1046537-A A kind of stable method of polyolefine that makes CIBA GEIGY AG (CH) 1990-10-31 CN disclosed