SCHEMBL9239126

SCHEMBL9239126

CC(C)(C)c1cc(C(CC(=O)OCC(COC(=O)CC(c2ccc(O)c(C(C)(C)C)c2)C(C)(C)C)(COC(=O)CC(c2ccc(O)c(C(C)(C)C)c2)C(C)(C)C)COC(=O)CC(c2ccc(O)c(C(C)(C)C)c2)C(C)(C)C)C(C)(C)C)ccc1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.39
GAA P10253 1/20 0.39
XBP1 P17861 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HSP90AA1 P07900 3/20 0.37
HSP90AB1 P08238 3/20 0.37
CYP2C9 P11712 2/20 0.37
HSD17B10 Q99714 2/20 0.37
NR1I2 O75469 1/20 0.37
LMNA P02545 1/20 0.37
MIF P14174 1/20 0.37
TYR P14679 1/20 0.37
ALOX15 P16050 1/20 0.37
HTT P42858 1/20 0.37
NFE2L2 Q16236 1/20 0.37
ESRRA P11474 2/20 0.36
NR1H4 Q96RI1 4/20 0.34
RARB P10826 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10447993 0.88 ATM (0.43) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL21629685 0.85 ALDH1A1 (0.41) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28729927 0.82 GAA (0.46) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL5617864 0.82 GAA (0.46) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL10276510 0.81 ALDH1A1 (0.38) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28311334 0.81 ALDH1A1 (0.43) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL7108338 0.81 ALDH1A1 (0.43) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL28287386 0.80 ALDH1A1 (0.42) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL6227382 0.79 GAA (0.39) ATMGAAXBP1NPSR1L3MBTL1
SCHEMBL30979216 0.79 ATM (0.42) ATMGAAXBP1NPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392392-B1 Method for stabilizing polyolefins CIBA GEIGY AG (CH) 1995-12-06 EP claimed
EP-0392392-B1 Method for stabilizing polyolefins CIBA GEIGY AG (CH) 1995-12-06 EP disclosed
US-5401845-A Asymmetric aryl phosphites CIBA-GEIGY CORPORATION (US) 1995-03-28 US disclosed
EP-0415887-B1 3-Phenyl-benzofuran-3-ones CIBA GEIGY AG (CH) 1994-10-05 EP disclosed
US-5340855-A Stabilizer for polymers CIBA-GEIGY CORPORATION (US) 1994-08-23 US disclosed
US-5322871-A Stabilize polymers against oxidation, thermal and photodegradation CIBA-GEIGY CORPORATION (US) 1994-06-21 US disclosed
US-5240622-A Mixture of a polymer, a lubricant, a metal working fluid or a hydraulic fluid and thermal, oxidative and/or actinic radiation stabilizer CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
US-5239076-A Processing stabilizer for polyethylene and polypropylene CIBA-GEIGY CORPORATION (US) 1993-08-24 US disclosed
US-5175312-A Radiation resistance CIBA-GEIGY CORPORATION (US) 1992-12-29 US disclosed
US-5132387-A Polyme bound ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-21 US disclosed
EP-0494639-A2 Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-15 EP disclosed
EP-0415887-A2 3-Phenyl-benzofuran-3-ones CIBA-GEIGY AG (CH) 1991-03-06 EP disclosed
EP-0392392-A1 Method for stabilizing polyolefins CIBA-GEIGY AG (CH) 1990-10-17 EP disclosed
US-4271063-A MELTING A BLEND OF POLYESTER AND ETHYLENE-VINYL ACETATE COPOLYMER AND FILLER GENERAL ELECTRIC COMPANY (US) 1981-06-02 US disclosed
EP-0016123-A4 IMPROVED REINFORCED THERMOPLASTIC MOLDING COMPOSITIONS. GEN ELECTRIC (US) 1980-11-14 EP disclosed
EP-0016123-A1 IMPROVED REINFORCED THERMOPLASTIC MOLDING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1980-10-01 EP disclosed
WO-1980000255-A1 IMPROVED REINFORCED THERMOPLASTIC MOLDING COMPOSITIONS GEN ELECTRIC (US) 1980-02-21 WO disclosed
US-4185047-A BLOCK POLYESTER COPOLYMER, OLEFIN POLYMER AND TALC; IMPROVED MOLD RELEASABILITY GENERAL ELECTRIC COMPANY (US) 1980-01-22 US disclosed
US-4101506-A PIPERIDINE COMPOUNDS, STABILIZERS FOR POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-4088629-A ADDING A PIPERIDINYL-GUANIDINE BAYER AKTIENGESELLSCHAFT (DT) 1978-05-09 US disclosed