Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274809 | 0.86 | CYP2C9 (0.52) | CYP2C9CYP2C19ANPEPTDP1MEN1 | |
| SCHEMBL5274814 | 0.86 | CYP2C9 (0.52) | CYP2C9CYP2C19ANPEPTDP1MEN1 | |
| SCHEMBL5674194 | 0.82 | TDP1 (0.48) | TDP1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL28169678 | 0.82 | TDP1 (0.48) | TDP1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL28169679 | 0.81 | TDP1 (0.47) | TDP1MEN1KMT2ASMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL8615330 | 0.80 | KMT2A (0.47) | CYP2C9CYP2C19MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7439899 | 0.78 | ELANE (0.44) | CYP2C9CYP2C19ANPEPMEN1KMT2A | |
| SCHEMBL7284516 | 0.78 | ANPEP (0.53) | ANPEPMEN1KMT2A | |
| SCHEMBL4179268 | 0.78 | CA2 (0.57) | KMT2ASMN1; SMN2CTSL | |
| SCHEMBL4179270 | 0.78 | CA2 (0.57) | KMT2ASMN1; SMN2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386611-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-12 | — | — | EP | disclosed |