Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22850232 | 0.89 | CYP11B1 (0.42) | CYP11B1CYP11B2SLC1A1FNTAFNTB | |
| SCHEMBL5171581 | 0.89 | SLC7A5 (0.47) | CYP11B1CYP11B2LTA4HSLC1A1NOS1 | |
| SCHEMBL5717739 | 0.87 | CYP11B1 (0.40) | CYP11B1CYP11B2LTA4HSLC1A1FNTA | |
| SCHEMBL5912748 | 0.87 | CYP11B1 (0.40) | CYP11B1CYP11B2LTA4HSLC1A1FNTA | |
| SCHEMBL6504426 | 0.86 | CYP11B1 (0.61) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8297235 | 0.86 | CYP11B1 (0.61) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL6504420 | 0.85 | CYP11B1 (0.60) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7431744 | 0.85 | CYP11B1 (0.36) | CYP11B1CYP11B2LTA4HSLC1A1FNTA | |
| SCHEMBL7278873 | 0.83 | CYP11B1 (0.37) | CYP11B1CYP11B2SLC1A1FNTAFNTB | |
| SCHEMBL10448610 | 0.80 | PTGES (0.40) | CYP11B1CYP11B2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386611-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-12 | — | — | EP | disclosed |