Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.61 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297235 | 1.00 | CYP11B1 (0.61) | CYP11B1CYP11B2FNTAFNTBACE2 | |
| Hydrochloric Acid SCHEMBL6504420 | 0.99 | CYP11B1 (0.60) | CYP11B1CYP11B2FNTAFNTBACE2 | |
| SCHEMBL10448124 | 0.86 | CYP11B1 (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL10397191 | 0.86 | CYP11B1 (0.55) | CYP11B1CYP11B2FNTAFNTBACE2 | |
| SCHEMBL8255653 | 0.86 | CYP11B1 (0.55) | CYP11B1CYP11B2FNTAFNTBACE2 | |
| SCHEMBL2224029 | 0.86 | ACE2 (0.58) | CYP11B1CYP11B2FNTAFNTBACE2 | |
| SCHEMBL2224035 | 0.86 | ACE2 (0.58) | CYP11B1CYP11B2FNTAFNTBACE2 | |
| SCHEMBL10448576 | 0.81 | CYP11B1 (0.42) | CYP11B1CYP11B2 | |
| SCHEMBL10448577 | 0.81 | CYP11B1 (0.42) | CYP11B1CYP11B2 | |
| SCHEMBL8248519 | 0.81 | CYP11B1 (0.56) | CYP11B1CYP11B2FNTAFNTBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |